Incorporating uracil and 5-halouracils into short peptide nucleic acids for enhanced recognition of A–U pairs in dsRNAs

Double-stranded RNA (dsRNA) structures form triplexes and RNA-protein complexes through binding to single-stranded RNA (ssRNA) regions and proteins, respectively, for diverse biological functions. Hence, targeting dsRNAs through major-groove triplex formation is a promising strategy for the developm...

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Detalles Bibliográficos
Autores principales: Patil, Kiran M, Toh, Desiree-Faye Kaixin, Yuan, Zhen, Meng, Zhenyu, Shu, Zhiyu, Zhang, Haiping, Ong, Alan Ann Lerk, Krishna, Manchugondanahalli S, Lu, Lanyuan, Lu, Yunpeng, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125629/
https://www.ncbi.nlm.nih.gov/pubmed/30011039
http://dx.doi.org/10.1093/nar/gky631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125629/
https://www.ncbi.nlm.nih.gov/pubmed/30011039
http://dx.doi.org/10.1093/nar/gky631

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