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Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR

The molecular mechanisms that underlie the neurological manifestations of patients with inherited diseases of vitamin B12 (cobalamin) metabolism remain to date obscure. We observed transcriptomic changes of genes involved in RNA metabolism and endoplasmic reticulum stress in a neuronal cell model wi...

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Detalles Bibliográficos
Autores principales:	Battaglia-Hsu, Shyue-Fang, Ghemrawi, Rose, Coelho, David, Dreumont, Natacha, Mosca, Pauline, Hergalant, Sébastien, Gauchotte, Guillaume, Sequeira, Jeffrey M, Ndiongue, Mariam, Houlgatte, Rémi, Alberto, Jean-Marc, Umoret, Remy, Robert, Aurélie, Paoli, Justine, Jung, Martin, Quadros, Edward V, Guéant, Jean-Louis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125644/ https://www.ncbi.nlm.nih.gov/pubmed/30016500 http://dx.doi.org/10.1093/nar/gky634

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