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Congenital diseases caused by defective O-glycosylation of Notch receptors
The Notch signaling pathway is highly conserved and essential for animal development. It is required for cell differentiation, survival, and proliferation. Regulation of Notch signaling is a crucial process for human health. Ligands initiate a signal cascade by binding to Notch receptors expressed o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nagoya University
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125653/ https://www.ncbi.nlm.nih.gov/pubmed/30214079 http://dx.doi.org/10.18999/nagjms.80.3.299 |