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Implementation of the CRISPR-Cas13a system in fission yeast and its repurposing for precise RNA editing
In contrast to genome editing, which introduces genetic changes at the DNA level, disrupting or editing gene transcripts provides a distinct approach to perturbing a genetic system, offering benefits complementary to classic genetic approaches. To develop a new toolset for manipulating RNA, we first...
Autores principales: | Jing, Xinyun, Xie, Bingran, Chen, Longxian, Zhang, Niubing, Jiang, Yiyi, Qin, Hang, Wang, Hongbing, Hao, Pei, Yang, Sheng, Li, Xuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125684/ https://www.ncbi.nlm.nih.gov/pubmed/29860393 http://dx.doi.org/10.1093/nar/gky433 |
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