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Implementation of the CRISPR-Cas13a system in fission yeast and its repurposing for precise RNA editing

In contrast to genome editing, which introduces genetic changes at the DNA level, disrupting or editing gene transcripts provides a distinct approach to perturbing a genetic system, offering benefits complementary to classic genetic approaches. To develop a new toolset for manipulating RNA, we first...

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Detalles Bibliográficos
Autores principales: Jing, Xinyun, Xie, Bingran, Chen, Longxian, Zhang, Niubing, Jiang, Yiyi, Qin, Hang, Wang, Hongbing, Hao, Pei, Yang, Sheng, Li, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125684/
https://www.ncbi.nlm.nih.gov/pubmed/29860393
http://dx.doi.org/10.1093/nar/gky433

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