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A tetracycline-inducible CRISPR/Cas9 system, targeting two long non-coding RNAs, suppresses the malignant behavior of bladder cancer cells

Clustered regularly interspaced short palindromic repeats (CRISPR) associated protein 9 (Cas9) technology has been applied in varied biological studies, including cancer studies. However, stable mRNA expression of Cas9 has potential risks in future gene therapy. Therefore, in the present study, a te...

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Detalles Bibliográficos
Autores principales: Peng, Lu, Pan, Peng, Chen, Jinbu, Yu, Xueyuan, Wu, Jun, Chen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126189/
https://www.ncbi.nlm.nih.gov/pubmed/30214566
http://dx.doi.org/10.3892/ol.2018.9157