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Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo

Generation of reactive oxygen species (ROS) has been shown to be important for many physiological processes, ranging from cell differentiation to apoptosis. With the development of the genetically encoded photosensitiser KillerRed (KR) it is now possible to efficiently produce ROS dose-dependently i...

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Detalles Bibliográficos
Autores principales: Formella, Isabel, Svahn, Adam J., Radford, Rowan A.W., Don, Emily K., Cole, Nicholas J., Hogan, Alison, Lee, Albert, Chung, Roger S., Morsch, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126400/
https://www.ncbi.nlm.nih.gov/pubmed/30193184
http://dx.doi.org/10.1016/j.redox.2018.08.011