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Log D analysis using dynamic approach
[Formula: see text] the logarithm ([Formula: see text]) of the distribution coefficient ([Formula: see text]), is one of the important parameters used in Lipinski's rule to assess the druggability of a molecule in pharmaceutical formulations. The distribution of a molecule between a hydrophobic...
Autores principales: | Krishnamoorthy, Ganeshkumar, Alluvada, Prashanth, Alemayehu, Esayas, Mohammed Sherieff, Shahul Hameed, Addi, Wasihun A., Kwa, Timothy, Krishnamoorthy, Janarthanan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126412/ https://www.ncbi.nlm.nih.gov/pubmed/30197931 http://dx.doi.org/10.1016/j.bbrep.2018.07.006 |
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