Cargando…

Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation (NIBS) method, which modulates the membrane potential of neurons in the cerebral cortex by a low-intensity direct current. tDCS is a low-cost technique with minimal adverse effects and easy application. This neurostim...

Descripción completa

Detalles Bibliográficos
Autores principales: Carvalho, Fabiana, Brietzke, Aline Patrícia, Gasparin, Assunta, dos Santos, Franciele Pereira, Vercelino, Rafael, Ballester, Rafael Firmino, Sanches, Paulo Roberto Stefani, da Silva, Danton Pereira, Torres, Iraci L. S., Fregni, Felipe, Caumo, Wolnei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126460/
https://www.ncbi.nlm.nih.gov/pubmed/30059026
http://dx.doi.org/10.3791/57614
_version_ 1783353333846638592
author Carvalho, Fabiana
Brietzke, Aline Patrícia
Gasparin, Assunta
dos Santos, Franciele Pereira
Vercelino, Rafael
Ballester, Rafael Firmino
Sanches, Paulo Roberto Stefani
da Silva, Danton Pereira
Torres, Iraci L. S.
Fregni, Felipe
Caumo, Wolnei
author_facet Carvalho, Fabiana
Brietzke, Aline Patrícia
Gasparin, Assunta
dos Santos, Franciele Pereira
Vercelino, Rafael
Ballester, Rafael Firmino
Sanches, Paulo Roberto Stefani
da Silva, Danton Pereira
Torres, Iraci L. S.
Fregni, Felipe
Caumo, Wolnei
author_sort Carvalho, Fabiana
collection PubMed
description Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation (NIBS) method, which modulates the membrane potential of neurons in the cerebral cortex by a low-intensity direct current. tDCS is a low-cost technique with minimal adverse effects and easy application. This neurostimulation method has a promising future to improve pain therapy, treatment of neuropsychiatric disorders, and physical rehabilitation. Current studies demonstrate the benefits of using tDCS over consecutive multiple sessions. However, the daily displacement to the specialized centers, travel costs, and disruptions to daily activities are some of the difficulties faced by patients. Thus, to be more comfortable, easy-to-use, and not disrupt daily commitments, a home-based tDCS was designed. Therefore, the objective of this study was to evaluate the feasibility of a portable tDCS device for home use in healthy subjects and fibromyalgia patients. Despite increased tDCS use and a reasonably large body of research on the effects across a range of clinical conditions, there is a limited amount of research on developing secure devices that guarantee the dose and contain a block system to avoid excessive use. Therefore, we used a tDCS device with a security system to permit daily use for 20 minutes with a minimal interval of 12 hours between sessions. A programmer preconfigures the equipment, which has a neoprene cap that allows the electrode positions in any assembly, according to individualized protocols for treatments or research. After, researchers can assess the effectiveness of treatment, and its adherence using information kept in the device software. Results suggest that the device is feasible for home use, with proper monitoring of adherence and contact impedance. There were reports of a few adverse effects, which do not differ from those reported in the literature in studies with the treatment under direct supervision.
format Online
Article
Text
id pubmed-6126460
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MyJove Corporation
record_format MEDLINE/PubMed
spelling pubmed-61264602018-09-19 Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients Carvalho, Fabiana Brietzke, Aline Patrícia Gasparin, Assunta dos Santos, Franciele Pereira Vercelino, Rafael Ballester, Rafael Firmino Sanches, Paulo Roberto Stefani da Silva, Danton Pereira Torres, Iraci L. S. Fregni, Felipe Caumo, Wolnei J Vis Exp Medicine Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation (NIBS) method, which modulates the membrane potential of neurons in the cerebral cortex by a low-intensity direct current. tDCS is a low-cost technique with minimal adverse effects and easy application. This neurostimulation method has a promising future to improve pain therapy, treatment of neuropsychiatric disorders, and physical rehabilitation. Current studies demonstrate the benefits of using tDCS over consecutive multiple sessions. However, the daily displacement to the specialized centers, travel costs, and disruptions to daily activities are some of the difficulties faced by patients. Thus, to be more comfortable, easy-to-use, and not disrupt daily commitments, a home-based tDCS was designed. Therefore, the objective of this study was to evaluate the feasibility of a portable tDCS device for home use in healthy subjects and fibromyalgia patients. Despite increased tDCS use and a reasonably large body of research on the effects across a range of clinical conditions, there is a limited amount of research on developing secure devices that guarantee the dose and contain a block system to avoid excessive use. Therefore, we used a tDCS device with a security system to permit daily use for 20 minutes with a minimal interval of 12 hours between sessions. A programmer preconfigures the equipment, which has a neoprene cap that allows the electrode positions in any assembly, according to individualized protocols for treatments or research. After, researchers can assess the effectiveness of treatment, and its adherence using information kept in the device software. Results suggest that the device is feasible for home use, with proper monitoring of adherence and contact impedance. There were reports of a few adverse effects, which do not differ from those reported in the literature in studies with the treatment under direct supervision. MyJove Corporation 2018-07-14 /pmc/articles/PMC6126460/ /pubmed/30059026 http://dx.doi.org/10.3791/57614 Text en Copyright © 2018, Journal of Visualized Experiments http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visithttp://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Medicine
Carvalho, Fabiana
Brietzke, Aline Patrícia
Gasparin, Assunta
dos Santos, Franciele Pereira
Vercelino, Rafael
Ballester, Rafael Firmino
Sanches, Paulo Roberto Stefani
da Silva, Danton Pereira
Torres, Iraci L. S.
Fregni, Felipe
Caumo, Wolnei
Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients
title Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients
title_full Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients
title_fullStr Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients
title_full_unstemmed Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients
title_short Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients
title_sort home-based transcranial direct current stimulation device development: an updated protocol used at home in healthy subjects and fibromyalgia patients
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126460/
https://www.ncbi.nlm.nih.gov/pubmed/30059026
http://dx.doi.org/10.3791/57614
work_keys_str_mv AT carvalhofabiana homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT brietzkealinepatricia homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT gasparinassunta homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT dossantosfrancielepereira homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT vercelinorafael homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT ballesterrafaelfirmino homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT sanchespaulorobertostefani homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT dasilvadantonpereira homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT torresiracils homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT fregnifelipe homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients
AT caumowolnei homebasedtranscranialdirectcurrentstimulationdevicedevelopmentanupdatedprotocolusedathomeinhealthysubjectsandfibromyalgiapatients