Utilizing (18)F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

A hallmark of advanced tumors is a switch to aerobic glycolysis that is readily measured by [(18)F]-2-fluoro-2-deoxy-D-glucose positron emission tomography ((18)F-FDG PET) imaging. Co-mutations in the KRAS proto-oncogene and the LKB1 tumor suppressor gene are frequent events in lung cancer that driv...

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Detalles Bibliográficos
Autores principales: Momcilovic, Milica, Bailey, Sean T., Lee, Jason T., Zamilpa, Charles, Jones, Anthony, Abdelhady, Gihad, Mansfield, James, Francis, Kevin P., Shackelford, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2018
Materias:
Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126521/
https://www.ncbi.nlm.nih.gov/pubmed/30080208
http://dx.doi.org/10.3791/57167

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