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Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents

RNA interference via the endogenous miRNA pathway regulates gene expression by controlling protein synthesis through post-transcriptional gene silencing. In recent years, miRNA-mediated gene regulation has shown potential for treatment of neurological disorders caused by a toxic gain of function mec...

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Detalles Bibliográficos
Autores principales:	Pourshafie, Naemeh, Lee, Philip R., Chen, Ke-lian, Harmison, George G., Bott, Laura C., Fischbeck, Kenneth H., Rinaldi, Carlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2018
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126683/ https://www.ncbi.nlm.nih.gov/pubmed/30148479 http://dx.doi.org/10.3791/55724

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