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A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and α(v)β(3) integrin for osteoporosis therapy
There is currently a demand for new highly efficient and specific drugs to treat osteoporosis, a chronic bone disease affecting millions of people worldwide. We have developed a combinatorial strategy for engineering bispecific inhibitors that simultaneously target the unique combination of c-FMS an...
Autores principales: | Zur, Yuval, Rosenfeld, Lior, Keshelman, Chen Anna, Dalal, Nofar, Guterman-Ram, Gali, Orenbuch, Ayelet, Einav, Yulia, Levaot, Noam, Papo, Niv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126843/ https://www.ncbi.nlm.nih.gov/pubmed/30142160 http://dx.doi.org/10.1371/journal.pbio.2002979 |
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