Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus

The role of integrin-mediated adhesion during T cell progenitor homing to and differentiation within the thymus is ill-defined, mainly due to functional overlap. To circumvent compensation, we disrupted the hematopoietic integrin regulator kindlin-3 in mice and found a progressive thymus atrophy tha...

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Detalles Bibliográficos
Autores principales: Moretti, Federico Andrea, Klapproth, Sarah, Ruppert, Raphael, Margraf, Andreas, Weber, Jasmin, Pick, Robert, Scheiermann, Christoph, Sperandio, Markus, Fässler, Reinhard, Moser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126919/
https://www.ncbi.nlm.nih.gov/pubmed/30187863
http://dx.doi.org/10.7554/eLife.35816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126919/
https://www.ncbi.nlm.nih.gov/pubmed/30187863
http://dx.doi.org/10.7554/eLife.35816

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