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Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus
The role of integrin-mediated adhesion during T cell progenitor homing to and differentiation within the thymus is ill-defined, mainly due to functional overlap. To circumvent compensation, we disrupted the hematopoietic integrin regulator kindlin-3 in mice and found a progressive thymus atrophy tha...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126919/ https://www.ncbi.nlm.nih.gov/pubmed/30187863 http://dx.doi.org/10.7554/eLife.35816 |