LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat

Increasing brown adipose tissue (BAT) thermogenesis in mice and humans improves metabolic health and understanding BAT function is of interest for novel approaches to counteract obesity. The role of long noncoding RNAs (lncRNAs) in these processes remains elusive. We observed maternally expressed, i...

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Detalles Bibliográficos
Autores principales: Schmidt, Elena, Dhaouadi, Ines, Gaziano, Isabella, Oliverio, Matteo, Klemm, Paul, Awazawa, Motoharu, Mitterer, Gerfried, Fernandez-Rebollo, Eduardo, Pradas-Juni, Marta, Wagner, Wolfgang, Hammerschmidt, Philipp, Loureiro, Rute, Kiefer, Christoph, Hansmeier, Nils R., Khani, Sajjad, Bergami, Matteo, Heine, Markus, Ntini, Evgenia, Frommolt, Peter, Zentis, Peter, Ørom, Ulf Andersson, Heeren, Jörg, Blüher, Matthias, Bilban, Martin, Kornfeld, Jan-Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127097/
https://www.ncbi.nlm.nih.gov/pubmed/30190464
http://dx.doi.org/10.1038/s41467-018-05933-8

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