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Convergence of sensory and limbic noxious input into the anterior insula and the emergence of pain from nociception
Two parallel di-synaptic routes convey nociceptive input to the telencephalon: the spino-thalamic system projecting principally to the posterior insula, and the spino-parabrachial pathway reaching the amygdalar nucleus. Interplay between the two systems underlies the sensory and emotional aspects of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127143/ https://www.ncbi.nlm.nih.gov/pubmed/30190593 http://dx.doi.org/10.1038/s41598-018-31781-z |