Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses

Expression of androgen receptor (AR) in prostate cancer (PCa) is heterogeneous but the functional significance of AR heterogeneity remains unclear. Screening ~200 castration-resistant PCa (CRPC) cores and whole-mount sections (from 89 patients) reveals 3 AR expression patterns: nuclear (nuc-AR), mix...

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Detalles Bibliográficos
Autores principales: Li, Qiuhui, Deng, Qu, Chao, Hsueh-Ping, Liu, Xin, Lu, Yue, Lin, Kevin, Liu, Bigang, Tang, Gregory W., Zhang, Dingxiao, Tracz, Amanda, Jeter, Collene, Rycaj, Kiera, Calhoun-Davis, Tammy, Huang, Jiaoti, Rubin, Mark A., Beltran, Himisha, Shen, Jianjun, Chatta, Gurkamal, Puzanov, Igor, Mohler, James L., Wang, Jianmin, Zhao, Ruizhe, Kirk, Jason, Chen, Xin, Tang, Dean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127155/
https://www.ncbi.nlm.nih.gov/pubmed/30190514
http://dx.doi.org/10.1038/s41467-018-06067-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127155/
https://www.ncbi.nlm.nih.gov/pubmed/30190514
http://dx.doi.org/10.1038/s41467-018-06067-7

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