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Replicative cellular age distributions in compartmentalized tissues
The cellular age distribution of hierarchically organized tissues can reveal important insights into the dynamics of cell differentiation and self-renewal and associated cancer risks. Here, we examine the effect of progenitor compartments with varying differentiation and self-renewal capacities on t...
Autores principales: | Böttcher, Marvin A., Dingli, David, Werner, Benjamin, Traulsen, Arne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127166/ https://www.ncbi.nlm.nih.gov/pubmed/30158183 http://dx.doi.org/10.1098/rsif.2018.0272 |
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