GATA2 zinc finger 1 mutations are associated with distinct clinico-biological features and outcomes different from GATA2 zinc finger 2 mutations in adult acute myeloid leukemia

Mutations of the GATA binding protein 2 (GATA2) gene in myeloid malignancies usually cluster in the zinc finger 1 (ZF1) and the ZF2 domains. Mutations in different locations of GATA2 may have distinct impact on clinico-biological features and outcomes in AML patients, but little is known in this asp...

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Detalles Bibliográficos
Autores principales: Tien, Feng-Ming, Hou, Hsin-An, Tsai, Cheng-Hong, Tang, Jih-Luh, Chiu, Yu-Chiao, Chen, Chien-Yuan, Kuo, Yuan-Yeh, Tseng, Mei-Hsuan, Peng, Yen-Ling, Liu, Ming-Chih, Liu, Chia-Wen, Liao, Xiu-Wen, Lin, Liang-In, Lin, Chien-Ting, Wu, Shang-Ju, Ko, Bor-Sheng, Hsu, Szu-Chun, Huang, Shang-Yi, Yao, Ming, Chou, Wen-Chien, Tien, Hwei-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127202/
https://www.ncbi.nlm.nih.gov/pubmed/30190467
http://dx.doi.org/10.1038/s41408-018-0123-2

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