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The DnaA AAA+ Domain His136 Residue Directs DnaB Replicative Helicase to the Unwound Region of the Replication Origin, oriC
Chromosomal replication initiation requires dynamic mechanisms in higher-order nucleoprotein complexes that are constructed at the origin of replication. In Escherichia coli, DnaA molecules construct functional oligomers at the origin oriC, enabling localized unwinding of oriC and stable binding of...
Autores principales: | Sakiyama, Yukari, Nishimura, Masahiro, Hayashi, Chihiro, Akama, Yusuke, Ozaki, Shogo, Katayama, Tsutomu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127211/ https://www.ncbi.nlm.nih.gov/pubmed/30233515 http://dx.doi.org/10.3389/fmicb.2018.02017 |
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