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Not All Immune Checkpoints Are Created Equal
Antibodies that block T cell inhibition via the immune checkpoints CTLA-4 and PD-1 have revolutionized cancer therapy during the last 15 years. T cells express additional inhibitory surface receptors that are considered to have potential as targets in cancer immunotherapy. Antibodies against LAG-3 a...
Autores principales: | De Sousa Linhares, Annika, Leitner, Judith, Grabmeier-Pfistershammer, Katharina, Steinberger, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127213/ https://www.ncbi.nlm.nih.gov/pubmed/30233564 http://dx.doi.org/10.3389/fimmu.2018.01909 |
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