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Functional Profiling of Chondrogenically Induced Multipotent Stromal Cell Aggregates Reveals Transcriptomic and Emergent Morphological Phenotypes Predictive of Differentiation Capacity
Multipotent stromal cells (MSCs) are an attractive cell source for bone and cartilage tissue repair strategies. However, the functional heterogeneity of MSCs derived from different donors and manufacturing conditions has limited clinical translation, emphasizing the need for improved methods to asse...
Autores principales: | Lam, Johnny, Bellayr, Ian H., Marklein, Ross A., Bauer, Steven R., Puri, Raj K., Sung, Kyung E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127231/ https://www.ncbi.nlm.nih.gov/pubmed/30084545 http://dx.doi.org/10.1002/sctm.18-0065 |
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