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In vitro and in vivo Pharmacological Activities of 14-O-Phenylpropyloxymorphone, a Potent Mixed Mu/Delta/Kappa-Opioid Receptor Agonist With Reduced Constipation in Mice

Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs. Opioids are the mainstay for the treatment of moderate to severe pain. Howev...

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Detalles Bibliográficos
Autores principales:	Lattanzi, Roberta, Rief, Silvia, Schmidhammer, Helmut, Negri, Lucia, Spetea, Mariana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127270/ https://www.ncbi.nlm.nih.gov/pubmed/30233377 http://dx.doi.org/10.3389/fphar.2018.01002

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