Cargando…

Turn Back the TIMe: Targeting Tumor Infiltrating Myeloid Cells to Revert Cancer Progression

Tumor cells frequently produce soluble factors that favor myelopoiesis and recruitment of myeloid cells to the tumor microenvironment (TME). Consequently, the TME of many cancer types is characterized by high infiltration of monocytes, macrophages, dendritic cells and granulocytes. Experimental and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Awad, Robin Maximilian, De Vlaeminck, Yannick, Maebe, Johannes, Goyvaerts, Cleo, Breckpot, Karine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127274/ https://www.ncbi.nlm.nih.gov/pubmed/30233579 http://dx.doi.org/10.3389/fimmu.2018.01977

Ejemplares similares

Cancer-Associated Myeloid Regulatory Cells
por: De Vlaeminck, Yannick, et al.
Publicado: (2016)

The Journey of in vivo Virus Engineered Dendritic Cells From Bench to Bedside: A Bumpy Road
por: Goyvaerts, Cleo, et al.
Publicado: (2018)

Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade
por: Lecocq, Quentin, et al.
Publicado: (2021)

TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy
por: De Ridder, Kirsten, et al.
Publicado: (2022)

In vitro modelling of local gene therapy with IL-15/IL-15Rα and a PD-L1 antagonist in melanoma reveals an interplay between NK cells and CD4(+) T cells
por: Awad, Robin Maximilian, et al.
Publicado: (2023)

Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma
por: De Beck, Lien, et al.
Publicado: (2022)

Pros and Cons of Antigen-Presenting Cell Targeted Tumor Vaccines
por: Goyvaerts, Cleo, et al.
Publicado: (2015)

Theranostics in immuno-oncology using nanobody derivatives
por: Lecocq, Quentin, et al.
Publicado: (2019)

Noninvasive Imaging of the Immune Checkpoint LAG-3 Using Nanobodies, from Development to Pre-Clinical Use
por: Lecocq, Quentin, et al.
Publicado: (2019)

Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development
por: De Vlaeminck, Yannick, et al.
Publicado: (2020)

Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade
por: Awad, Robin Maximilian, et al.
Publicado: (2021)

Targeted Radionuclide Therapy with Low and High-Dose Lutetium-177–Labeled Single Domain Antibodies Induces Distinct Immune Signatures in a Mouse Melanoma Model
por: Ertveldt, Thomas, et al.
Publicado: (2022)

Junctional adhesion molecule-A is dispensable for myeloid cell recruitment and diversification in the tumor microenvironment
por: Kiss, Máté, et al.
Publicado: (2022)

Perforin and Granzyme B Expressed by Murine Myeloid-Derived Suppressor Cells: A Study on Their Role in Outgrowth of Cancer Cells
por: Dufait, Inès, et al.
Publicado: (2019)

Editorial: Rising stars in cancer immunity and immunotherapy 2022
por: Goyvaerts, Cleo, et al.
Publicado: (2023)

Assessing T-cell responses in anticancer immunotherapy: Dendritic cells or myeloid-derived suppressor cells?
por: Escors, David, et al.
Publicado: (2013)

Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGIT
por: Zeven, Katty, et al.
Publicado: (2023)

The prognostic value and therapeutic targeting of myeloid-derived suppressor cells in hematological cancers
por: Fan, Rong, et al.
Publicado: (2022)

Transcutaneous Vagal Nerve Stimulation Alone or in Combination With Radiotherapy Stimulates Lung Tumor Infiltrating Lymphocytes But Fails to Suppress Tumor Growth
por: Reijmen, Eva, et al.
Publicado: (2021)

Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8(+) T cell and iNKT cell activating mRNA vaccine
por: Ertveldt, Thomas, et al.
Publicado: (2023)

Unraveling the Effects of a Talimogene Laherparepvec (T-VEC)-Induced Tumor Oncolysate on Myeloid Dendritic Cells
por: Tijtgat, Jens, et al.
Publicado: (2021)

Assessing Tumor-Infiltrating Lymphocytes in Breast Cancer: A Proposal for Combining Immunohistochemistry and Gene Expression Analysis to Refine Scoring
por: Locy, Hanne, et al.
Publicado: (2022)

Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer
por: Lecocq, Q., et al.
Publicado: (2021)

Human Tumor-Infiltrating Myeloid Cells: Phenotypic and Functional Diversity
por: Elliott, Louise A., et al.
Publicado: (2017)

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon
por: Broos, Katrijn, et al.
Publicado: (2016)

The Inhibition of Caspase-1- Does Not Revert Particulate Matter (PM)-Induced Lung Immunesuppression in Mice
por: Colarusso, Chiara, et al.
Publicado: (2019)

Complex Stability and an Irrevertible Transition Reverted by Peptide and Fibroblasts in a Dynamic Model of Innate Immunity
por: Abudukelimu, Abulikemu, et al.
Publicado: (2020)

Editorial: The immunosuppressive tumor microenvironment and strategies to revert its immune regulatory milieu for cancer immunotherapy
por: Ganjalikhani Hakemi, Mazdak, et al.
Publicado: (2023)

Immunogenicity of targeted lentivectors
por: Goyvaerts, Cleo, et al.
Publicado: (2014)

Targeting the tumor microenvironment to enhance antitumor immune responses
por: Van der Jeught, Kevin, et al.
Publicado: (2014)

Hepatocarcinoma Induces a Tumor Necrosis Factor-Dependent Kupffer Cell Death Pathway That Favors Its Proliferation Upon Partial Hepatectomy
por: Hastir, Jean-François, et al.
Publicado: (2020)

Repolarization of Tumor-Infiltrating Myeloid Cells for Augmentation of CAR T Cell Therapies
por: Luo, Weichuan, et al.
Publicado: (2022)

Mycobacterium tuberculosis-Specific T Cell Functional, Memory, and Activation Profiles in QuantiFERON-Reverters Are Consistent With Controlled Infection
por: Mpande, Cheleka A. M., et al.
Publicado: (2021)

Turning back an invasion
por: Dove, Alan W.
Publicado: (2001)

Relapsing–Remitting Multiple Sclerosis Is Characterized by a T Follicular Cell Pro-Inflammatory Shift, Reverted by Dimethyl Fumarate Treatment
por: Cunill, Vanesa, et al.
Publicado: (2018)

Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
por: Toor, Salman M., et al.
Publicado: (2016)

Mixing Signals: Molecular Turn Ons and Turn Offs for Innate γδ T-Cells
por: Bekiaris, Vasileios, et al.
Publicado: (2014)

Will It Revert to Pageantry and Burlesque?
Publicado: (1920)

Tilt back to turn left
por: Wells, William A.
Publicado: (2004)

Turn back, wayward axon
por: Leslie, Mitch
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_ms5hvm6uvkrktuu2tases9s6p9