Cargando…
In vitro Models for Seizure-Liability Testing Using Induced Pluripotent Stem Cells
The brain is the most complex organ in the body, controlling our highest functions, as well as regulating myriad processes which incorporate the entire physiological system. The effects of prospective therapeutic entities on the brain and central nervous system (CNS) may potentially cause significan...
Autores principales: | Grainger, Alastair I., King, Marianne C., Nagel, David A., Parri, H. Rheinallt, Coleman, Michael D., Hill, Eric J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127295/ https://www.ncbi.nlm.nih.gov/pubmed/30233290 http://dx.doi.org/10.3389/fnins.2018.00590 |
Ejemplares similares
-
Novel test strategies for in vitro seizure liability assessment
por: Tukker, Anke M., et al.
Publicado: (2021) -
Assessing seizure liability in vitro with voltage-sensitive dye imaging in mouse hippocampal slices
por: Utsumi, Yuichi, et al.
Publicado: (2023) -
A requirement for astrocyte IP(3)R2 signaling for whisker experience-dependent depression and homeostatic upregulation in the mouse barrel cortex
por: Butcher, John B., et al.
Publicado: (2022) -
NT2 Derived Neuronal and Astrocytic Network Signalling
por: Hill, Eric J., et al.
Publicado: (2012) -
A Predictive In Vitro Model of the Impact of Drugs with Anticholinergic Properties on Human Neuronal and Astrocytic Systems
por: Woehrling, Elizabeth K., et al.
Publicado: (2015)