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Design and characterisation of a dissolving microneedle patch for intradermal vaccination with heat-inactivated bacteria: A proof of concept study
This work describes the formulation and evaluation of dissolving microneedle patches (MNs) for intradermal delivery of heat-inactivated bacteria. Pseudomonas aeruginosa, strain PA01, was used as a model bacterium. Utilising a simple, cost effective fabrication process, P. aeruginosa was heat-inactiv...
Autores principales: | Rodgers, Aoife M., McCrudden, Maelíosa T.C., Vincente-Perez, Eva.M., Dubois, Alice V., Ingram, Rebecca J., Larrañeta, Eneko, Kissenpfennig, Adrien, Donnelly, Ryan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland Biomedical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127419/ https://www.ncbi.nlm.nih.gov/pubmed/30048778 http://dx.doi.org/10.1016/j.ijpharm.2018.07.049 |
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