Cargando…

Postoperative Bio-Chemoradiotherapy Using Cetuximab and Docetaxel in Patients With Cis-Platinum–Intolerant Core High-Risk Head and Neck Cancer: Protocol of a Phase 2 Nonrandomized Clinical Trial

BACKGROUND: We confirmed the safety of postoperative bio-chemoradiotherapy using cetuximab and docetaxel in a small number of patients with cis-platinum–intolerant core high-risk head and neck cancer. OBJECTIVE: To assess treatment efficacy, we planned a phase 2 study of postoperative bio-chemoradio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nishimura, Goshi, Hatakeyama, Hiromitsu, Shiono, Osamu, Taguri, Masataka, Komatsu, Masanori, Sano, Daisuke, Sakuma, Naoko, Yabuki, Kenichiro, Arai, Yasuhiro, Shibata, Kunihiko, Chiba, Yoshihiro, Tanabe, Teruhiko, Oridate, Nobuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JMIR Publications 2018
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127497/ https://www.ncbi.nlm.nih.gov/pubmed/30139721 http://dx.doi.org/10.2196/11003

Ejemplares similares

The Second-Look Procedure for Transoral Videolaryngoscopic Surgery for T1 and T2 Laryngeal, Oropharyngeal, and Hypopharyngeal Cancer Patients: Protocol for a Nonrandomized Clinical Trial
por: Nishimura, Goshi, et al.
Publicado: (2017)

Predictive and Prognostic Value of Metabolic Tumor Volume (MTV) in Patients with Laryngeal Carcinoma Treated by Radiotherapy (RT) / Concurrent Chemoradiotherapy (CCRT)
por: Yabuki, Kenichiro, et al.
Publicado: (2015)

A prospective clinical trial of the second‐look procedure for transoral surgery in patients with T1 and T2 laryngeal, oropharyngeal, and hypopharyngeal cancer
por: Nishimura, Goshi, et al.
Publicado: (2019)

Intraductal Carcinoma of the Parotid Gland Presenting as Parapharyngeal Mass
por: Oki, Yamato, et al.
Publicado: (2020)

A first case report of nasopharyngeal Mycobacterium abscessus subspecies massiliense infection
por: Oki, Yamato, et al.
Publicado: (2021)

Validity of intraoperative voice monitoring undergoing type 2 thyroplasty with titanium bridges for adductor spasmodic dysphonia
por: Sanuki, Tetsuji, et al.
Publicado: (2022)

Docetaxel plus cetuximab as second-line treatment for docetaxel-refractory oesophagogastric cancer: the AGITG ATTAX2 trial
por: Tebbutt, N C, et al.
Publicado: (2013)

Maintenance ramucirumab monotherapy after intolerable toxicities following docetaxel plus ramucirumab
por: Hata, Akito, et al.
Publicado: (2018)

Randomized Phase II Trial of Irinotecan/Docetaxel or Irinotecan/Docetaxel Plus Cetuximab for Metastatic Pancreatic Cancer: An Eastern Cooperative Oncology Group Study
por: Burtness, Barbara, et al.
Publicado: (2016)

Weekly Docetaxel, Cisplatin, and Cetuximab in Palliative Treatment of Patients with Squamous Cell Carcinoma of the Head and Neck
por: Trieu, Vanessa, et al.
Publicado: (2018)

Feasibility of Induction Docetaxel, Cisplatin, 5-Fluorouracil, Cetuximab (TPF-C) Followed by Concurrent Cetuximab Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
por: Charalambakis, Nikolaos, et al.
Publicado: (2013)

Pretreatment prognostic factor for patients with human papillomavirus related oropharyngeal cancer
por: Sano, Daisuke, et al.
Publicado: (2019)

Long-term efficacy of immune checkpoint inhibitors with or without chemotherapy in recurrent or metastatic squamous cell carcinoma of the head and neck: a commentary on the 4-year follow-up of the KEYNOTE-048 trial
por: Sano, Daisuke, et al.
Publicado: (2023)

Clinical significance of primary prophylactic pegylated‐granulocyte‐colony stimulating factor after the administration of ramucirumab plus docetaxel in patients with previously treated non‐small cell lung cancer
por: Mouri, Atsuto, et al.
Publicado: (2019)

Establishment of experimental salivary gland cancer models using organoid culture and patient-derived xenografting
por: Aizawa, Yoshihiro, et al.
Publicado: (2022)

Docetaxel plus cetuximab biweekly is an active regimen for the first-line treatment of patients with recurrent/metastatic head and neck cancer
por: Posch, Doris, et al.
Publicado: (2016)

In vivo evaluation of cetuximab-conjugated poly(γ-glutamic acid)-docetaxel nanomedicines in EGFR-overexpressing gastric cancer xenografts
por: Sreeranganathan, Maya, et al.
Publicado: (2017)

Long-Term Survival of Patients With Chemotherapy-Naïve Metastatic Nasopharyngeal Carcinoma Receiving Cetuximab Plus Docetaxel and Cisplatin Regimen
por: Zhang, Mengping, et al.
Publicado: (2020)

First-line cisplatin, docetaxel, and cetuximab for patients with recurrent or metastatic head and neck cancer: A multicenter cohort study
por: Falco, Agustín, et al.
Publicado: (2022)

Improved efficacy of ramucirumab plus docetaxel after nivolumab failure in previously treated non‐small cell lung cancer patients
por: Shiono, Ayako, et al.
Publicado: (2019)

Long‐term treatment outcome of type 1 thyroplasty using novel titanium medialization laryngoplasty implant combined with arytenoid adduction for unilateral vocal cord paralysis: single‐arm interventional study at a single institution
por: Sano, Daisuke, et al.
Publicado: (2020)

Modified biweekly cisplatin, docetaxel plus cetuximab (TPEx) as first-line treatment for patients with recurrent/metastatic head and neck cancer
por: Fuchs, Hannah, et al.
Publicado: (2018)

In vivo evaluation of cetuximab-conjugated poly(γ-glutamic acid)-docetaxel nanomedicines in EGFR-overexpressing gastric cancer xenografts [Corrigendum]
Publicado: (2019)

A Multicenter Phase II Trial of Docetaxel, Cisplatin, and Cetuximab (TPEx) Followed by Cetuximab and Concurrent Radiotherapy for Patients With Local Advanced Squamous Cell Carcinoma of the Head and Neck (CSPOR HN01: ECRIPS Study)
por: Zenda, Sadamoto, et al.
Publicado: (2019)

Phase II study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study)
por: Pinto, C, et al.
Publicado: (2009)

Pathogenic Role of Immune Evasion and Integration of Human Papillomavirus in Oropharyngeal Cancer
por: Hatano, Takashi, et al.
Publicado: (2021)

Nonrandom network connectivity comes in pairs
por: Hoffmann, Felix Z., et al.
Publicado: (2017)

An effective screening strategy for deafness in combination with a next-generation sequencing platform: a consecutive analysis
por: Sakuma, Naoko, et al.
Publicado: (2016)

Daily Cisplatin and Weekly Docetaxel versus Weekly Cisplatin Intra-Arterial Chemoradiotherapy for Late T2-3 Tongue Cancer: A Pilot and Feasibility Trial
por: Hayashi, Yuichiro, et al.
Publicado: (2018)

Real impact of liver cirrhosis on the development of hepatocellular carcinoma in various liver diseases—meta‐analytic assessment
por: Tarao, Kazuo, et al.
Publicado: (2019)

Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma
por: Fertig, Elana J, et al.
Publicado: (2012)

Botulinum toxin injection into the intrinsic laryngeal muscles to treat spasmodic dysphonia: A multicenter, placebo‐controlled, randomized, double‐blinded, parallel‐group comparison/open‐label clinical trial
por: Hyodo, Masamitsu, et al.
Publicado: (2021)

Sensitivity Analysis in Nonrandomized Longitudinal Mediation Analysis
por: Tofighi, Davood
Publicado: (2021)

A Phase II Clinical Trial of Concurrent Helical Tomotherapy plus Cetuximab Followed by Adjuvant Chemotherapy with Cisplatin and Docetaxel for Locally Advanced Nasopharyngeal Carcinoma
por: Zhang, Xinxin, et al.
Publicado: (2016)

Nonrandom chromosome arrangements in germ line nuclei of Sciara coprophila males: the basis for nonrandom chromosome segregation on the meiosis I spindle
Publicado: (1987)

Growth Inhibition of Head and Neck Squamous Cell Carcinoma Cells by sgRNA Targeting the Cyclin D1 mRNA Based on TRUE Gene Silencing
por: Iizuka, Satoshi, et al.
Publicado: (2014)

Sequential administration of PD‑1 inhibitor and cetuximab causes pneumonia
por: Arai, Makoto, et al.
Publicado: (2023)

Real impact of tumor marker AFP and PIVKA-II in detecting very small hepatocellular carcinoma (≤ 2 cm, Barcelona stage 0) - assessment with large number of cases
por: Tarao, Kazuo, et al.
Publicado: (2020)

Clinical Outcomes of First Subsequent Therapies After Abiraterone Acetate Plus Prednisone for High-Risk Metastatic Castration-Sensitive Prostate Cancer in the LATITUDE Study
por: Koroki, Yosuke, et al.
Publicado: (2022)

Analysis of feasibility and toxicity of concurrent chemoradiotherapy with S-1 for locally advanced squamous cell carcinoma of the head and neck in elderly cases and/or cases with comorbidity
por: Tsukuda, Mamoru, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_2mrdb6c61gspg1hiugni5t7nf5