Peroxynitrite Exposure of CXCL12 Impairs Monocyte, Lymphocyte and Endothelial Cell Chemotaxis, Lymphocyte Extravasation in vivo and Anti-HIV-1 Activity

CXCL12 is a chemotactic cytokine that attracts many different cell types for homeostasis and during inflammation. Under stress conditions, macrophages and granulocytes produce factors such as peroxynitrite as a consequence of their oxidative response. After short incubations of CXCL12 with peroxynit...

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Detalles Bibliográficos
Autores principales: Janssens, Rik, Boff, Daiane, Ruytinx, Pieter, Mortier, Anneleen, Vanheule, Vincent, Larsen, Olav, Daugvilaite, Viktorija, Rosenkilde, Mette M., Noppen, Sam, Liekens, Sandra, Schols, Dominique, De Meester, Ingrid, Opdenakker, Ghislain, Struyf, Sofie, Teixeira, Mauro M., Amaral, Flávio A., Proost, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127631/
https://www.ncbi.nlm.nih.gov/pubmed/30233568
http://dx.doi.org/10.3389/fimmu.2018.01933

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