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The structure of 9-(3-bromo-6-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­ethyl)-3,6-diphenyl-3,4,5,6,7,9-hexa­hydro-2H-acridine-1,8-dione

In the structure of the title compound C(33)H(29)BrClNO(4), (I), the hexa­hydro-2H-acridine ring system has a hy­droxy­ethyl substituent on the N atom and a 3-bromo-6-chloro-2-hy­droxy­phenyl substituent on the central C atom at the 9-position. An unusual feature of the mol­ecule is that the substit...

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Autores principales: Abdelhamid, Antar A., Hawaiz, Farouq E., Mohamed, Alaa F., Mohamed, Shaaban K., Simpson, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127693/
https://www.ncbi.nlm.nih.gov/pubmed/30225103
http://dx.doi.org/10.1107/S2056989018010873
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author Abdelhamid, Antar A.
Hawaiz, Farouq E.
Mohamed, Alaa F.
Mohamed, Shaaban K.
Simpson, Jim
author_facet Abdelhamid, Antar A.
Hawaiz, Farouq E.
Mohamed, Alaa F.
Mohamed, Shaaban K.
Simpson, Jim
author_sort Abdelhamid, Antar A.
collection PubMed
description In the structure of the title compound C(33)H(29)BrClNO(4), (I), the hexa­hydro-2H-acridine ring system has a hy­droxy­ethyl substituent on the N atom and a 3-bromo-6-chloro-2-hy­droxy­phenyl substituent on the central C atom at the 9-position. An unusual feature of the mol­ecule is that the substituents at the 3- and 5-positions of the outer cyclo­hexenone rings are phenyl rings rather than the more common dimethyl substituents. C atoms on both of the cyclo­hexenone rings are disordered over two sites. In the crystal structure, O—H⋯O, C—H⋯O and C—H⋯π(ring) hydrogen bonds combine with an Br—O and unusual C—Br⋯π(ring) halogen bonds to generate a three dimensional network with mol­ecules stacked along the a-axis direction.
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spelling pubmed-61276932018-09-17 The structure of 9-(3-bromo-6-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­ethyl)-3,6-diphenyl-3,4,5,6,7,9-hexa­hydro-2H-acridine-1,8-dione Abdelhamid, Antar A. Hawaiz, Farouq E. Mohamed, Alaa F. Mohamed, Shaaban K. Simpson, Jim Acta Crystallogr E Crystallogr Commun Research Communications In the structure of the title compound C(33)H(29)BrClNO(4), (I), the hexa­hydro-2H-acridine ring system has a hy­droxy­ethyl substituent on the N atom and a 3-bromo-6-chloro-2-hy­droxy­phenyl substituent on the central C atom at the 9-position. An unusual feature of the mol­ecule is that the substituents at the 3- and 5-positions of the outer cyclo­hexenone rings are phenyl rings rather than the more common dimethyl substituents. C atoms on both of the cyclo­hexenone rings are disordered over two sites. In the crystal structure, O—H⋯O, C—H⋯O and C—H⋯π(ring) hydrogen bonds combine with an Br—O and unusual C—Br⋯π(ring) halogen bonds to generate a three dimensional network with mol­ecules stacked along the a-axis direction. International Union of Crystallography 2018-08-14 /pmc/articles/PMC6127693/ /pubmed/30225103 http://dx.doi.org/10.1107/S2056989018010873 Text en © Abdelhamid et al. 2018 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/2.0/uk/
spellingShingle Research Communications
Abdelhamid, Antar A.
Hawaiz, Farouq E.
Mohamed, Alaa F.
Mohamed, Shaaban K.
Simpson, Jim
The structure of 9-(3-bromo-6-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­ethyl)-3,6-diphenyl-3,4,5,6,7,9-hexa­hydro-2H-acridine-1,8-dione
title The structure of 9-(3-bromo-6-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­ethyl)-3,6-diphenyl-3,4,5,6,7,9-hexa­hydro-2H-acridine-1,8-dione
title_full The structure of 9-(3-bromo-6-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­ethyl)-3,6-diphenyl-3,4,5,6,7,9-hexa­hydro-2H-acridine-1,8-dione
title_fullStr The structure of 9-(3-bromo-6-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­ethyl)-3,6-diphenyl-3,4,5,6,7,9-hexa­hydro-2H-acridine-1,8-dione
title_full_unstemmed The structure of 9-(3-bromo-6-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­ethyl)-3,6-diphenyl-3,4,5,6,7,9-hexa­hydro-2H-acridine-1,8-dione
title_short The structure of 9-(3-bromo-6-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­ethyl)-3,6-diphenyl-3,4,5,6,7,9-hexa­hydro-2H-acridine-1,8-dione
title_sort structure of 9-(3-bromo-6-chloro-2-hy­droxy­phen­yl)-10-(2-hy­droxy­ethyl)-3,6-diphenyl-3,4,5,6,7,9-hexa­hydro-2h-acridine-1,8-dione
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127693/
https://www.ncbi.nlm.nih.gov/pubmed/30225103
http://dx.doi.org/10.1107/S2056989018010873
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