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All three IP(3) receptor subtypes generate Ca(2+) puffs, the universal building blocks of IP(3)-evoked Ca(2+) signals

All three subtypes of inositol 1,4,5-trisphosphate receptor (IP(3)R) are intracellular Ca(2+) channels that are co-regulated by IP(3) and Ca(2+). This allows IP(3)Rs to evoke regenerative Ca(2+) signals, the smallest of which are Ca(2+) puffs that reflect the coordinated opening of a few clustered I...

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Detalles Bibliográficos
Autores principales: Mataragka, Stefania, Taylor, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127726/
https://www.ncbi.nlm.nih.gov/pubmed/30097556
http://dx.doi.org/10.1242/jcs.220848