The new H(2)S-releasing compound ACS94 exerts protective effects through the modulation of thiol homoeostasis

The synthesis of a new dithiolethione-cysteine ethyl ester hybrid, ACS94, its metabolites, and its effect on GSH levels in rat tissues and on the concentration of circulating H(2)S is described. ACS94 rapidly enters the cells, where it is metabolised to cysteine and the dithiolethione moiety ACS48....

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Detalles Bibliográficos
Autores principales: Giustarini, Daniela, Tazzari, Valerio, Bassanini, Ivan, Rossi, Ranieri, Sparatore, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127811/
https://www.ncbi.nlm.nih.gov/pubmed/30173573
http://dx.doi.org/10.1080/14756366.2018.1509211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127811/
https://www.ncbi.nlm.nih.gov/pubmed/30173573
http://dx.doi.org/10.1080/14756366.2018.1509211

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