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Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting

Glioblastoma is the most common malignant brain tumor. Efficient delivery of drugs targeting glioblastomas remains a challenge. Ephrin type-A receptor 3 (EPHA3) tyrosine kinase antibody-modified polylactide-co-glycolide (PLGA) nanoparticles (NPs) were developed to target glioblastoma via nose-to-bra...

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Detalles Bibliográficos
Autores principales:	Chu, Liuxiang, Wang, Aiping, Ni, Ling, Yan, Xiuju, Song, Yina, Zhao, Mingyu, Sun, Kaoxiang, Mu, Hongjie, Liu, Sha, Wu, Zimei, Zhang, Chunyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127843/ https://www.ncbi.nlm.nih.gov/pubmed/30176744 http://dx.doi.org/10.1080/10717544.2018.1494226

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