Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer’s drug candidates

A new series of multifunctional hybrids, based on the structure of the donepezil (DNP) drug, have been developed and evaluated as potential anti Alzheimer’s disease (AD) agents. The rationale of this study was the conjugation of a benzylpiperidine/benzylpiperazine moiety with derivatives of bioactiv...

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Detalles Bibliográficos
Autores principales: Piemontese, Luca, Tomás, Daniel, Hiremathad, Asha, Capriati, Vito, Candeias, Emanuel, Cardoso, Sandra M., Chaves, Sílvia, Santos, M. Amélia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127844/
https://www.ncbi.nlm.nih.gov/pubmed/30160188
http://dx.doi.org/10.1080/14756366.2018.1491564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127844/
https://www.ncbi.nlm.nih.gov/pubmed/30160188
http://dx.doi.org/10.1080/14756366.2018.1491564

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