Cargando…
Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer’s drug candidates
A new series of multifunctional hybrids, based on the structure of the donepezil (DNP) drug, have been developed and evaluated as potential anti Alzheimer’s disease (AD) agents. The rationale of this study was the conjugation of a benzylpiperidine/benzylpiperazine moiety with derivatives of bioactiv...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127844/ https://www.ncbi.nlm.nih.gov/pubmed/30160188 http://dx.doi.org/10.1080/14756366.2018.1491564 |