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A versatile drug delivery system targeting senescent cells
Senescent cells accumulate in multiple aging‐associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal β‐galactosidase activity of senescent cells to design a drug delivery system based on the encapsulatio...
Autores principales: | Muñoz‐Espín, Daniel, Rovira, Miguel, Galiana, Irene, Giménez, Cristina, Lozano‐Torres, Beatriz, Paez‐Ribes, Marta, Llanos, Susana, Chaib, Selim, Muñoz‐Martín, Maribel, Ucero, Alvaro C, Garaulet, Guillermo, Mulero, Francisca, Dann, Stephen G, VanArsdale, Todd, Shields, David J, Bernardos, Andrea, Murguía, José Ramón, Martínez‐Máñez, Ramón, Serrano, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127887/ https://www.ncbi.nlm.nih.gov/pubmed/30012580 http://dx.doi.org/10.15252/emmm.201809355 |
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