Cargando…

Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study

BACKGROUND: Although there is a recognition of the importance of fertility to young women with cancer, we do not know who is at risk of distress related to fertility issues following diagnosis. We investigated the determinants of fertility-related distress adopting a cross-cultural perspective and u...

Descripción completa

Detalles Bibliográficos
Autores principales: Sobota, Aleksandra, Ozakinci, Gozde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127915/
https://www.ncbi.nlm.nih.gov/pubmed/30189847
http://dx.doi.org/10.1186/s12885-018-4766-y
_version_ 1783353555828080640
author Sobota, Aleksandra
Ozakinci, Gozde
author_facet Sobota, Aleksandra
Ozakinci, Gozde
author_sort Sobota, Aleksandra
collection PubMed
description BACKGROUND: Although there is a recognition of the importance of fertility to young women with cancer, we do not know who is at risk of distress related to fertility issues following diagnosis. We investigated the determinants of fertility-related distress adopting a cross-cultural perspective and using the Common Sense Model (CSM). We chose the CSM as a theoretical framework as it allows to explore how individuals conceptualise illness within the socio-cultural context. METHODS: British and Polish women with breast or gynaecological cancer were recruited through outpatient clinics or online outlets and completed a questionnaire. Linear regression, mediation and moderated mediation methods were performed. RESULTS: One hundred sixty-four women participated (mean age 34.55 (SD = 6.66); 78.7% had gynaecological cancer). The determinants of fertility-related distress were: country of origin, recruitment site, negative affect, desire to have children, treatment regret, and total illness perception score. The impact of the desire to have children on fertility-related distress was mediated by psychological value of children, perceived consequences of cancer on one’s life, emotional representation, and treatment-related regret. Country of origin moderated the relationship between the desire to have children and fertility-related distress when mediated by treatment-related regret. CONCLUSIONS: The CSM proved useful in investigating predictors of fertility-related distress, with emotional, rather than cognitive representation of illness determining its levels. Socio-cultural background played a role in determining one’s fertility-related distress and contributed to the explanation of the relationship between one’s desire to have children, treatment-related regret, and fertility-related distress. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12885-018-4766-y) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-6127915
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-61279152018-09-10 Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study Sobota, Aleksandra Ozakinci, Gozde BMC Cancer Research Article BACKGROUND: Although there is a recognition of the importance of fertility to young women with cancer, we do not know who is at risk of distress related to fertility issues following diagnosis. We investigated the determinants of fertility-related distress adopting a cross-cultural perspective and using the Common Sense Model (CSM). We chose the CSM as a theoretical framework as it allows to explore how individuals conceptualise illness within the socio-cultural context. METHODS: British and Polish women with breast or gynaecological cancer were recruited through outpatient clinics or online outlets and completed a questionnaire. Linear regression, mediation and moderated mediation methods were performed. RESULTS: One hundred sixty-four women participated (mean age 34.55 (SD = 6.66); 78.7% had gynaecological cancer). The determinants of fertility-related distress were: country of origin, recruitment site, negative affect, desire to have children, treatment regret, and total illness perception score. The impact of the desire to have children on fertility-related distress was mediated by psychological value of children, perceived consequences of cancer on one’s life, emotional representation, and treatment-related regret. Country of origin moderated the relationship between the desire to have children and fertility-related distress when mediated by treatment-related regret. CONCLUSIONS: The CSM proved useful in investigating predictors of fertility-related distress, with emotional, rather than cognitive representation of illness determining its levels. Socio-cultural background played a role in determining one’s fertility-related distress and contributed to the explanation of the relationship between one’s desire to have children, treatment-related regret, and fertility-related distress. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12885-018-4766-y) contains supplementary material, which is available to authorized users. BioMed Central 2018-09-06 /pmc/articles/PMC6127915/ /pubmed/30189847 http://dx.doi.org/10.1186/s12885-018-4766-y Text en © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Sobota, Aleksandra
Ozakinci, Gozde
Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study
title Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study
title_full Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study
title_fullStr Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study
title_full_unstemmed Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study
title_short Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study
title_sort determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127915/
https://www.ncbi.nlm.nih.gov/pubmed/30189847
http://dx.doi.org/10.1186/s12885-018-4766-y
work_keys_str_mv AT sobotaaleksandra determinantsoffertilityissuesexperiencedbyyoungwomendiagnosedwithbreastorgynaecologicalcanceraquantitativecrossculturalstudy
AT ozakincigozde determinantsoffertilityissuesexperiencedbyyoungwomendiagnosedwithbreastorgynaecologicalcanceraquantitativecrossculturalstudy