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Topical steroid versus placebo for the prevention of radiation dermatitis in head and neck cancer patients receiving chemoradiotherapy: the study protocol of J-SUPPORT 1602 (TOPICS study), a randomized double-blinded phase 3 trial

BACKGROUND: To date, the clinical benefit of topical steroid use has only been demonstrated for radiation dermatitis induced by 50–60 Gy irradiation in breast cancer. However, these agents are also often used clinically for the control of radiation dermatitis induced by high-dose (>60Gy) irradiat...

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Detalles Bibliográficos
Autores principales: Zenda, Sadamoto, Yamaguchi, Takuhiro, Yokota, Tomoya, Miyaji, Tempei, Mashiko, Tomoe, Tanaka, Mari, Yonemura, Masahito, Takeno, Misaki, Okano, Tomoka, Kawasaki, Toshikatsu, Nakamori, Yuko, Ishii, Shinobu, Shimada, Sanae, Kanamaru, Miyuki, Uchitomi, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127935/
https://www.ncbi.nlm.nih.gov/pubmed/30189840
http://dx.doi.org/10.1186/s12885-018-4763-1