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Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma

BACKGROUND: Human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) has an improved outcome and may allow for treatment de-escalation. High-risk HPV (HR-HPV) infection is associated with deregulated expression of the cell cycle-associated proteins p16(INK4), pRB, cyclin D1 a...

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Detalles Bibliográficos
Autores principales:	Plath, Michaela, Broglie, Martina A., Förbs, Diana, Stoeckli, Sandro J., Jochum, Wolfram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127938/ https://www.ncbi.nlm.nih.gov/pubmed/30189895 http://dx.doi.org/10.1186/s40463-018-0298-3

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