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Inhibition of STAT3 in gastric cancer: role of pantoprazole as SHP-1 inducer

BACKGROUND: We investigated the inhibitory effect of pantoprazole on signal transducer and activator of transcription 3 (STAT3) activity and invasiveness of gastric adenocarcinoma cells, and the role of SH2-containing protein tyrosine phosphatase 1 (SHP-1) in mediating role. METHODS: We used AGS and...

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Detalles Bibliográficos
Autores principales: Koh, Jin Sung, Joo, Moon Kyung, Park, Jong-Jae, Yoo, Hyo Soon, Choi, Byung Il, Lee, Beom Jae, Chun, Hoon Jai, Lee, Sang Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127946/
https://www.ncbi.nlm.nih.gov/pubmed/30202514
http://dx.doi.org/10.1186/s13578-018-0248-9