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Involvement of Akt/CREB signaling pathways in the protective effect of EPA against interleukin-1β-induced cytotoxicity and BDNF down-regulation in cultured rat hippocampal neurons

BACKGROUND: Our published data have indicated that the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) provides beneficial effects by attenuating neuronal damage induced by interleukin-1β (IL-1β), and up-regulation of the expression of brain-derived neurotrophic factor (BDNF) represen...

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Detalles Bibliográficos
Autores principales:	Dong, YiLong, Pu, KangJing, Duan, WenJing, Chen, HuiCheng, Chen, LiXing, Wang, YanMei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128001/ https://www.ncbi.nlm.nih.gov/pubmed/30189852 http://dx.doi.org/10.1186/s12868-018-0455-7

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