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F.E.M. Stress-Investigation of Scolios Apex

BACKGROUND: In scoliosis, kypholordos and wedge properties of the vertebrae should be involved in determining how stress is distributed in the vertebral column. The impact is logically expected to be maximal at the apex. AIM: To introduce an algorithm for constructing artificial geometric models of...

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Autores principales: Daghighi, A., Tropp, H., Dahlström, N., Klarbring, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128020/
https://www.ncbi.nlm.nih.gov/pubmed/30258499
http://dx.doi.org/10.2174/1874120701812010051
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author Daghighi, A.
Tropp, H.
Dahlström, N.
Klarbring, A.
author_facet Daghighi, A.
Tropp, H.
Dahlström, N.
Klarbring, A.
author_sort Daghighi, A.
collection PubMed
description BACKGROUND: In scoliosis, kypholordos and wedge properties of the vertebrae should be involved in determining how stress is distributed in the vertebral column. The impact is logically expected to be maximal at the apex. AIM: To introduce an algorithm for constructing artificial geometric models of the vertebral column from DICOM stacks, with the ultimate aim to obtain a formalized way to create simplistic models, which enhance and focus on wedge properties and relative tilting. MATERIAL/METHODS: Our procedure requires parameter extraction from DICOM image-stacks (with PACS,IDS-7), mechanical FEM-modelling (with Matlab and Comsol). As a test implementation, models were constructed for five patients with thoracal idiopathic scoliosis with varying apex rotation. For a selection of load states, we calculated a response variable which is based upon distortion energy. RESULTS: For the test implementation, pairwise t-tests show that our response variable is non-trivial and that it is chiefly sensitive to the transversal stresses (transversal stresses where of main interest to us, as opposed to the case of additional shear stresses, due to the lack of explicit surrounding tissue and ligaments in our model). Also, a pairwise t-test did not show a difference (n = 25, p-value≈0.084) between the cases of isotropic and orthotropic material modeling. CONCLUSION: A step-by-step description is given for a procedure of constructing artificial geometric models from chest CT DICOM-stacks, such that the models are appropriate for semi-global stress-analysis, where the focus is on the wedge properties and relative tilting. The method is inappropriate for analyses where the local roughness and irregularities of surfaces are wanted features. A test application hints that one particular load state possibly has a high correlation to a certain response variable (based upon distortion energy distribution on a surface of the apex), however, the number of patients is too small to draw any statistical conclusions.
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spelling pubmed-61280202018-09-26 F.E.M. Stress-Investigation of Scolios Apex Daghighi, A. Tropp, H. Dahlström, N. Klarbring, A. Open Biomed Eng J Biomedical Engineering BACKGROUND: In scoliosis, kypholordos and wedge properties of the vertebrae should be involved in determining how stress is distributed in the vertebral column. The impact is logically expected to be maximal at the apex. AIM: To introduce an algorithm for constructing artificial geometric models of the vertebral column from DICOM stacks, with the ultimate aim to obtain a formalized way to create simplistic models, which enhance and focus on wedge properties and relative tilting. MATERIAL/METHODS: Our procedure requires parameter extraction from DICOM image-stacks (with PACS,IDS-7), mechanical FEM-modelling (with Matlab and Comsol). As a test implementation, models were constructed for five patients with thoracal idiopathic scoliosis with varying apex rotation. For a selection of load states, we calculated a response variable which is based upon distortion energy. RESULTS: For the test implementation, pairwise t-tests show that our response variable is non-trivial and that it is chiefly sensitive to the transversal stresses (transversal stresses where of main interest to us, as opposed to the case of additional shear stresses, due to the lack of explicit surrounding tissue and ligaments in our model). Also, a pairwise t-test did not show a difference (n = 25, p-value≈0.084) between the cases of isotropic and orthotropic material modeling. CONCLUSION: A step-by-step description is given for a procedure of constructing artificial geometric models from chest CT DICOM-stacks, such that the models are appropriate for semi-global stress-analysis, where the focus is on the wedge properties and relative tilting. The method is inappropriate for analyses where the local roughness and irregularities of surfaces are wanted features. A test application hints that one particular load state possibly has a high correlation to a certain response variable (based upon distortion energy distribution on a surface of the apex), however, the number of patients is too small to draw any statistical conclusions. Bentham Open 2018-07-31 /pmc/articles/PMC6128020/ /pubmed/30258499 http://dx.doi.org/10.2174/1874120701812010051 Text en © 2018 Daghighi et al. https://creativecommons.org/licenses/by/4.0/legalcode This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Biomedical Engineering
Daghighi, A.
Tropp, H.
Dahlström, N.
Klarbring, A.
F.E.M. Stress-Investigation of Scolios Apex
title F.E.M. Stress-Investigation of Scolios Apex
title_full F.E.M. Stress-Investigation of Scolios Apex
title_fullStr F.E.M. Stress-Investigation of Scolios Apex
title_full_unstemmed F.E.M. Stress-Investigation of Scolios Apex
title_short F.E.M. Stress-Investigation of Scolios Apex
title_sort f.e.m. stress-investigation of scolios apex
topic Biomedical Engineering
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128020/
https://www.ncbi.nlm.nih.gov/pubmed/30258499
http://dx.doi.org/10.2174/1874120701812010051
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