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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
This manuscript presents a step-by-step protocol for screening compounds at gamma-aminobutyric acid type A (GABA(A)) receptors and its use towards the identification of novel molecules active in preclinical assays from an in vitro recombinant receptor to their pharmacological effects at native recep...
Autores principales: | Knoflach, Frédéric, Hernandez, Maria-Clemencia, Bertrand, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128072/ https://www.ncbi.nlm.nih.gov/pubmed/30175997 http://dx.doi.org/10.3791/57842 |
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