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Tumor Heterogeneity in Primary Colorectal Cancer and Corresponding Metastases. Does the Apple Fall Far From the Tree?

Colorectal cancer harbors tremendous heterogeneity, with temporal and spatial differences in genetic mutations, epigenetic regulation, and tumor microenvironment. Analyzing the distribution and frequency of genetic, epigenetic, and microenvironment differences within a given tumor and between differ...

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Detalles Bibliográficos
Autores principales:	Blank, Annika, Roberts, Daniel Edward, Dawson, Heather, Zlobec, Inti, Lugli, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128217/ https://www.ncbi.nlm.nih.gov/pubmed/30234115 http://dx.doi.org/10.3389/fmed.2018.00234

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