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Cytotoxic Necrotizing Factor 1 Downregulates CD36 Transcription in Macrophages to Induce Inflammation During Acute Urinary Tract Infections

Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) induce cystitis, pyelonephritis, and can cause kidney scarring and failure if inflammation is not under control. The detailed effects of cytotoxic necrotizing factor 1 (CNF1), the key UPEC toxin, on the pathogenicity of...

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Detalles Bibliográficos
Autores principales:	Yang, Huan, Li, Qianqian, Wang, Changying, Wang, Jingyu, Lv, Junqiang, Wang, Lei, Zhang, Zhi-Song, Yao, Zhi, Wang, Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128224/ https://www.ncbi.nlm.nih.gov/pubmed/30233583 http://dx.doi.org/10.3389/fimmu.2018.01987

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