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Discovery of the Novel Entecavir‐Resistant Hepatitis B Virus Reverse Transcriptase A181C Substitution From an Integrated Genotypic Analysis

Entecavir (ETV) is a first‐line therapy for chronic hepatitis B virus (HBV), demonstrating potent suppression of HBV DNA and a high barrier to viral resistance. Previous studies revealed that ETV‐resistant (ETVr) HBV DNA resulted from substitutions in the HBV reverse transcriptase (RT) at positions...

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Detalles Bibliográficos
Autores principales:	Rose, Ronald E., Hernandez, Dennis, Falk, Paul J., Ericson, Karen, Zhou, Nannan, Thiry, Alexandra, McPhee, Fiona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128232/ https://www.ncbi.nlm.nih.gov/pubmed/30202825 http://dx.doi.org/10.1002/hep4.1231

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