Cargando…

Whole‐Exome Sequencing Study of Extreme Phenotypes of NAFLD

Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous disease with highly variable outcomes. Patients with simple steatosis typically experience a benign course, whereas those with more advanced liver injury, nonalcoholic steatohepatitis (NASH), and advanced stage fibrosis suffer increased ris...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kleinstein, Sarah E., Rein, Matthew, Abdelmalek, Manal F., Guy, Cynthia D., Goldstein, David B., Mae Diehl, Anna, Moylan, Cynthia A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128233/ https://www.ncbi.nlm.nih.gov/pubmed/30202817 http://dx.doi.org/10.1002/hep4.1227

Ejemplares similares

Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD
por: Wegermann, Kara, et al.
Publicado: (2021)

Serum Bile Acid, Vitamin E, and Serotonin Metabolites Are Associated With Future Liver‐Related Events in Nonalcoholic Fatty Liver Disease
por: Wegermann, Kara, et al.
Publicado: (2021)

Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study
por: Wegermann, Kara, et al.
Publicado: (2018)

Serum Metabolites Are Associated With HFpEF in Biopsy‐Proven Nonalcoholic Fatty Liver Disease
por: Wegermann, Kara, et al.
Publicado: (2023)

Whole exome sequencing of extreme age-related macular degeneration phenotypes
por: Sardell, Rebecca J., et al.
Publicado: (2016)

Serum Interleukin‐8, Osteopontin, and Monocyte Chemoattractant Protein 1 Are Associated With Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease
por: Glass, Oliver, et al.
Publicado: (2018)

Perceptions of Exercise and Its Challenges in Patients With Nonalcoholic Fatty Liver Disease: A Survey‐Based Study
por: Glass, Oliver, et al.
Publicado: (2021)

Whole‐exome and HLA sequencing in Febrile infection‐related epilepsy syndrome
por: Helbig, Ingo, et al.
Publicado: (2020)

Whole‐exome sequencing analysis of juvenile papillomatosis and coexisting breast carcinoma
por: D'Alfonso, Timothy M, et al.
Publicado: (2020)

Glycemic Control Predicts Severity of Hepatocyte Ballooning and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease
por: Alexopoulos, Anastasia‐Stefania, et al.
Publicado: (2021)

The use of whole-exome sequencing to disentangle complex phenotypes
por: Williams, Hywel J, et al.
Publicado: (2016)

Platform comparison of detecting copy number variants with microarrays and whole-exome sequencing
por: de Ligt, Joep, et al.
Publicado: (2014)

Lifting the lid on unborn lethal Mendelian phenotypes through exome sequencing
por: Shamseldin, Hanan E., et al.
Publicado: (2013)

Deep learning-based quantification of NAFLD/NASH progression in human liver biopsies
por: Heinemann, Fabian, et al.
Publicado: (2022)

Identification of candidate genes and pathways in retinopathy of prematurity by whole exome sequencing of preterm infants enriched in phenotypic extremes
por: Kim, Sang Jin, et al.
Publicado: (2021)

Nonspecific phenotype of Noonan syndrome diagnosed by whole exome sequencing
por: Coromilas, Alexandra, et al.
Publicado: (2015)

Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression
por: Du, Kuo, et al.
Publicado: (2019)

Identification of Two Cases of Ciliopathy-Associated Diabetes and Their Mutation Analysis Using Whole Exome Sequencing
por: Kim, Min Kyeong, et al.
Publicado: (2015)

Whole-exome sequencing for a more accurate diagnosis of intraductal papillary neoplasms of the bile duct
por: Matsumori, Tomoaki, et al.
Publicado: (2021)

Whole-exome sequencing exploration of acquired uniparental disomies in B-cell precursor acute lymphoblastic leukemia
por: Lundin-Ström, Kristina B., et al.
Publicado: (2018)

Identification of Maturity-Onset Diabetes of the Young Caused by Glucokinase Mutations Detected Using Whole-Exome Sequencing
por: Cho, Eun-Hee, et al.
Publicado: (2017)

Association of liver fibrosis risk scores with clinical outcomes in patients with heart failure with preserved ejection fraction: findings from TOPCAT
por: Peters, Anthony E., et al.
Publicado: (2021)

Whole Exome Sequencing in Patients with Phenotypically Associated Familial Intracranial Aneurysm
por: Song, Yunsun, et al.
Publicado: (2022)

Whole exome sequencing characterization of individuals presenting extreme phenotypes of high and low risk of developing tobacco-induced lung adenocarcinoma
por: Patiño-García, Ana, et al.
Publicado: (2021)

Exome Sequencing as a Diagnostic Tool for Pediatric-Onset Ataxia
por: Sawyer, Sarah L, et al.
Publicado: (2014)

Whole exome sequencing in the rat
por: Foley, Julie F., et al.
Publicado: (2018)

Whole-Exome Sequencing to Identify Potential Genetic Risk in Substance Use Disorders: A Pilot Feasibility Study
por: AshaRani, P. V., et al.
Publicado: (2021)

Whole-exome sequencing of 228 patients with sporadic Parkinson’s disease
por: Sandor, Cynthia, et al.
Publicado: (2017)

Screening the human exome: a comparison of whole genome and whole transcriptome sequencing
por: Cirulli, Elizabeth T, et al.
Publicado: (2010)

Whole exome sequencing as a diagnostic tool for patients with ciliopathy-like phenotypes
por: Castro-Sánchez, Sheila, et al.
Publicado: (2017)

A MT-TL1 variant identified by whole exome sequencing in an individual with intellectual disability, epilepsy, and spastic tetraparesis
por: de Boer, Elke, et al.
Publicado: (2021)

Whole-exome sequencing detected a novel AIFM1 variant in a Han-Chinese family with Cowchock syndrome
por: Wang, Chenyu, et al.
Publicado: (2023)

Whole Exome Sequencing of Extreme Morbid Obesity Patients: Translational Implications for Obesity and Related Disorders
por: Paz-Filho, Gilberto, et al.
Publicado: (2014)

Whole-Exome Sequencing in Congenital Hypothyroidism Due to Thyroid Dysgenesis
por: Larrivée-Vanier, Stéphanie, et al.
Publicado: (2022)

Whole Exome Sequencing in Atrial Fibrillation
por: Lubitz, Steven A., et al.
Publicado: (2016)

Whole-exome sequencing study of hypospadias
por: Chen, Zhongzhong, et al.
Publicado: (2023)

Whole-Exome Sequencing Revealing Somatic NLRP3 Mosaicism in a Patient With Chronic Infantile Neurologic, Cutaneous, Articular Syndrome
por: Omoyinmi, Ebun, et al.
Publicado: (2014)

Whole-exome sequencing of fibroblast and its iPS cell lines derived from a patient diagnosed with xeroderma pigmentosum
por: Okamura, Kohji, et al.
Publicado: (2015)

Identification of a Novel Mutation of LAMB3 Gene in a Lybian Patient with Hereditary Epidermolysis Bullosa by Whole Exome Sequencing
por: Laroussi, Nadia, et al.
Publicado: (2017)

Whole-exome sequencing of long-term, never relapse exceptional responders of trastuzumab-treated HER2+ metastatic breast cancer
por: Walsh, Naomi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_b0vooqs8asotft0rbi62ovdepa