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GDF11 induces differentiation and apoptosis and inhibits migration of C17.2 neural stem cells via modulating MAPK signaling pathway

GDF11, a member of TGF-β superfamily, has recently received widespread attention as a novel anti-ageing/rejuvenation factor to reverse age-related dysfunctions in heart and skeletal muscle, and to induce angiogenesis and neurogenesis. However, these positive effects of GDF11 were challenged by sever...

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Detalles Bibliográficos
Autores principales: Wang, Zongkui, Dou, Miaomiao, Liu, Fengjuan, Jiang, Peng, Ye, Shengliang, Ma, Li, Cao, Haijun, Du, Xi, Sun, Pan, Su, Na, Lin, Fangzhao, Zhang, Rong, Li, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128255/
https://www.ncbi.nlm.nih.gov/pubmed/30202652
http://dx.doi.org/10.7717/peerj.5524