Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screening

Patients diagnosed with glioblastoma (GBM) continue to face a bleak prognosis. It is critical that new effective therapeutic strategies are developed. GBM stem cells have molecular hallmarks of neural stem and progenitor cells and it is possible to propagate both non-transformed normal neural stem c...

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Detalles Bibliográficos
Autores principales: O'Duibhir, Eoghan, Carragher, Neil O., Pollard, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128397/
https://www.ncbi.nlm.nih.gov/pubmed/27825983
http://dx.doi.org/10.1016/j.mcn.2016.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128397/
https://www.ncbi.nlm.nih.gov/pubmed/27825983
http://dx.doi.org/10.1016/j.mcn.2016.11.001

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