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Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screening
Patients diagnosed with glioblastoma (GBM) continue to face a bleak prognosis. It is critical that new effective therapeutic strategies are developed. GBM stem cells have molecular hallmarks of neural stem and progenitor cells and it is possible to propagate both non-transformed normal neural stem c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128397/ https://www.ncbi.nlm.nih.gov/pubmed/27825983 http://dx.doi.org/10.1016/j.mcn.2016.11.001 |