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Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes

Dengue virus (DENV), an arthropod-borne (“arbovirus”) virus, causes a range of human maladies ranging from self-limiting dengue fever to the life-threatening dengue shock syndrome and proliferates well in two different taxa of the Animal Kingdom, mosquitoes and primates. Mosquitoes and primates show...

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Detalles Bibliográficos
Autores principales:	Stauft, Charles B., Shen, Sam H., Song, Yutong, Gorbatsevych, Oleksandr, Asare, Emmanuel, Futcher, Bruce, Mueller, Steffen, Payne, Anne, Brecher, Matthew, Kramer, Laura, Wimmer, Eckard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128446/ https://www.ncbi.nlm.nih.gov/pubmed/30192757 http://dx.doi.org/10.1371/journal.pone.0198303

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