A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD)

The Semi-solid Control Diagram (SSCD) is a new tool designed for the study of different excipients and different semi-solid dosage forms. It can be used to review and evaluate different formulations and/or batches and facilitate the selection of one of them that will present the most suitable galeni...

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Autores principales: Nardi-Ricart, Anna, Linares, Maria Jose, Villca-Pozo, Faviola, Pérez-Lozano, Pilar, Suñé-Negre, Josep Maria, Bachs-deMiquel, Lara, Roig-Carreras, Manel, Suñé-Pou, Marc, Nofrerias-Roig, Isaac, García-Montoya, Encarna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128454/
https://www.ncbi.nlm.nih.gov/pubmed/30192759
http://dx.doi.org/10.1371/journal.pone.0201643
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author Nardi-Ricart, Anna
Linares, Maria Jose
Villca-Pozo, Faviola
Pérez-Lozano, Pilar
Suñé-Negre, Josep Maria
Bachs-deMiquel, Lara
Roig-Carreras, Manel
Suñé-Pou, Marc
Nofrerias-Roig, Isaac
García-Montoya, Encarna
author_facet Nardi-Ricart, Anna
Linares, Maria Jose
Villca-Pozo, Faviola
Pérez-Lozano, Pilar
Suñé-Negre, Josep Maria
Bachs-deMiquel, Lara
Roig-Carreras, Manel
Suñé-Pou, Marc
Nofrerias-Roig, Isaac
García-Montoya, Encarna
author_sort Nardi-Ricart, Anna
collection PubMed
description The Semi-solid Control Diagram (SSCD) is a new tool designed for the study of different excipients and different semi-solid dosage forms. It can be used to review and evaluate different formulations and/or batches and facilitate the selection of one of them that will present the most suitable galenic characteristics for topical application. It is also useful to track stability studies by comparing the diagrams, which allows to measure the impact of subjecting the formulation to different conditions and times to be examined. In this study, the Semi-solid Control Diagram (SSCD) is used as an instrument for studying and evaluating semi-solid pharmaceutical dosage forms, by comparing several different semisolid preparations (lipogels). With these results, the tool is validated and the best formulation has been discriminated from the others.
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spelling pubmed-61284542018-09-15 A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD) Nardi-Ricart, Anna Linares, Maria Jose Villca-Pozo, Faviola Pérez-Lozano, Pilar Suñé-Negre, Josep Maria Bachs-deMiquel, Lara Roig-Carreras, Manel Suñé-Pou, Marc Nofrerias-Roig, Isaac García-Montoya, Encarna PLoS One Research Article The Semi-solid Control Diagram (SSCD) is a new tool designed for the study of different excipients and different semi-solid dosage forms. It can be used to review and evaluate different formulations and/or batches and facilitate the selection of one of them that will present the most suitable galenic characteristics for topical application. It is also useful to track stability studies by comparing the diagrams, which allows to measure the impact of subjecting the formulation to different conditions and times to be examined. In this study, the Semi-solid Control Diagram (SSCD) is used as an instrument for studying and evaluating semi-solid pharmaceutical dosage forms, by comparing several different semisolid preparations (lipogels). With these results, the tool is validated and the best formulation has been discriminated from the others. Public Library of Science 2018-09-07 /pmc/articles/PMC6128454/ /pubmed/30192759 http://dx.doi.org/10.1371/journal.pone.0201643 Text en © 2018 Nardi-Ricart et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Nardi-Ricart, Anna
Linares, Maria Jose
Villca-Pozo, Faviola
Pérez-Lozano, Pilar
Suñé-Negre, Josep Maria
Bachs-deMiquel, Lara
Roig-Carreras, Manel
Suñé-Pou, Marc
Nofrerias-Roig, Isaac
García-Montoya, Encarna
A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD)
title A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD)
title_full A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD)
title_fullStr A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD)
title_full_unstemmed A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD)
title_short A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD)
title_sort new design for the review and appraisal of semi-solid dosage forms: semi-solid control diagram (sscd)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128454/
https://www.ncbi.nlm.nih.gov/pubmed/30192759
http://dx.doi.org/10.1371/journal.pone.0201643
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